Some other translations say "do not grieve the Holy Spirit." Two truths scream to be heard. First, the way we live matters deeply to the Spirit! Second, we can actually oppose and wound the Spirit of God who lives in us. As Galatians 5:13-21 reminds us, feeding the fleshly, sinful side of ourselves puts us at war with the Spirit of God. Things like telling lies to each other, acting out our anger, stealing, sharing unwholesome talk among ourselves, living with rage and brawling, and slander are all activities that bring the Holy Spirit sorrow (Ephesians 4:25-32). Living under the influence of the Spirit empowers us to go beyond these bad qualities as we are conformed to be more and more like Jesus (2 Corinthians 3:18; Galatians 5:22-26).
Sovereign God, I confess that I sometimes ignore the impulse of the Holy Spirit inside of me and act in ways that are inconsistent and hurtful to you. I want to be like Jesus — more and more under the influence and control of your Holy Spirit. Please open my eyes to your will, your presence, and your character as the Spirit leads me.